When people talk about cannabis, the conversation usually centers on THC and CBD. And for good reason—these two cannabinoids are the most abundant and most researched. But here’s the thing: THC and CBD are just the tip of the iceberg.
Beneath the surface lies a vast world of “minor cannabinoids”—compounds like CBG (cannabigerol), CBN (cannabinol), CBC (cannabichromene) and more—that might be small in quantity, but big in potential.
In this post, we’re diving into what makes minor cannabinoids so special, how they work in harmony through the entourage effect, and why full-spectrum cannabis products are gaining serious momentum in wellness circles.
So... What Are Minor Cannabinoids?
Let’s start with the basics.
Cannabis contains over 100 cannabinoids, and each one interacts with your body in a slightly different way. Most people are familiar with:
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THC (tetrahydrocannabinol): the compound responsible for the psychoactive "high"
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CBD (cannabidiol): known for its calming and anti-inflammatory effects
But there’s a lot more going on behind the scenes.
Meet the Minors
Here are a few minor cannabinoids you should know about:
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CBG (Cannabigerol) – Often called the "mother of all cannabinoids," CBG is the precursor from which other cannabinoids are synthesized.
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CBN (Cannabinol) – A mildly psychoactive cannabinoid that forms as THC degrades; it’s often linked to sedative effects.
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CBC (Cannabichromene) – Believed to play a role in mood regulation and inflammation.
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THCV (Tetrahydrocannabivarin) – Known for its energizing and appetite-suppressing qualities.
These minor cannabinoids may exist in small amounts in most cannabis strains, but their effects can be powerful—and in some cases, even more targeted than THC or CBD alone.
CBG: The Unsung Hero
Let’s zoom in on CBG, one of the rising stars of the cannabinoid world.
Why is CBG Called the “Mother Cannabinoid”?
CBG is the first cannabinoid the cannabis plant produces in its early growth stages. As the plant matures, CBG is converted into other cannabinoids like THC, CBD, and CBC. That’s why mature cannabis plants usually only have trace amounts of CBG—around 1% or less.
What Are the Benefits of CBG?
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Anti-inflammatory properties: CBG has shown promise in treating conditions like IBD (Inflammatory Bowel Disease) and colitis.
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Neuroprotective effects: Early research suggests CBG may help protect brain cells in conditions like Huntington’s disease.
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Antibacterial agent: Some studies have found CBG to be highly effective against resistant bacteria like MRSA.
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Mood support: Like CBD, CBG interacts with the endocannabinoid system (ECS) to regulate mood and stress.
CBG products are now emerging in oils, capsules, and even infused beverages—and for good reason. While more research is needed, CBG has exciting potential as a non-intoxicating cannabinoid with targeted therapeutic benefits.
CBN: The Sleepytime Cannabinoid
Next up: CBN, a cannabinoid that’s gaining traction in the wellness world, especially among folks who struggle with sleep.
Where Does CBN Come From?
CBN is actually a byproduct of THC. Over time, THC exposed to oxygen and heat breaks down and becomes CBN. So if you’ve ever had some really old weed lying around and felt it made you sleepy? That’s likely the CBN at work.
What Can CBN Do?
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Sleep support: CBN is often marketed as a natural sleep aid, especially when combined with CBD or melatonin.
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Pain relief: It may have mild analgesic properties when used in tandem with other cannabinoids.
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Appetite stimulation: While THC is the go-to for munchies, CBN also seems to encourage appetite.
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Anti-inflammatory: Like many cannabinoids, CBN shows promise for reducing inflammation.
It’s important to note that CBN is not a sedative on its own—at least not strongly so. But it seems to enhance sedative effects when combined with other cannabinoids, which brings us to our next point.
The Entourage Effect: Why Cannabinoids Work Better Together
One of the most fascinating discoveries in cannabis science is the entourage effect—a term first coined by Israeli researchers in the late ‘90s.
What Is the Entourage Effect?
The entourage effect refers to the synergistic relationship between all the compounds in cannabis: cannabinoids, terpenes, flavonoids, and more. When taken together, these compounds amplify each other’s therapeutic effects.
Think of it like a band: THC might be the lead singer, but the minor cannabinoids, terpenes, and other plant compounds are the backup vocals and rhythm section. Alone, they’re fine. Together, they’re magic.
Why This Matters
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CBG may enhance the pain-relieving qualities of CBD.
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CBN may deepen the relaxation effects of THC.
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Terpenes like myrcene or linalool can boost sedative effects when paired with cannabinoids.
This is one of the biggest arguments in favor of full-spectrum cannabis products, which contain a wide array of cannabinoids and terpenes—not just THC or CBD in isolation.
Full-Spectrum vs. Broad-Spectrum vs. Isolate
If you’ve spent time shopping for cannabis or hemp-derived products, you’ve probably come across these terms:
Full-Spectrum
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Contains all cannabinoids, including trace amounts of THC (up to 0.3% in legal hemp products)
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Preserves the entourage effect
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Best for people who want a whole-plant experience
Broad-Spectrum
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Includes many cannabinoids, but no THC
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Still allows for some entourage benefits
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Good for people who want to avoid THC completely (e.g., for drug testing reasons)
Isolate
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Pure single compound (e.g., pure CBD or pure CBN)
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No entourage effect
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Often used in research or highly targeted applications
For most people looking to get the full benefit of cannabis compounds, full-spectrum is the way to go. It’s the closest thing to consuming the whole plant in a natural, balanced form.
The Future of Minor Cannabinoids
As the cannabis industry matures and consumer interest expands beyond THC and CBD, we’re entering an exciting new era of cannabinoid customization.
Imagine:
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A CBG-forward beverage for focus and clarity
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A CBN-infused gummy for deep, restorative sleep
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A CBC topical for mood support and skin inflammation
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THCV capsules for appetite control and clean energy
Many of these products already exist—and more are on the way as research continues and regulation evolves.
Final Thoughts: Minor Cannabinoids, Major Benefits
It’s time we stop thinking of CBG, CBN, and other “minor” cannabinoids as, well, minor. These compounds are essential to the full power of the cannabis plant, and they’re only beginning to be understood.
By embracing full-spectrum cannabis, you’re not just getting THC or CBD—you’re getting a rich, complex blend of natural compounds that work together to help your body find balance, calm, and clarity.
So next time you're browsing the dispensary shelf or researching a new tincture, don’t just look at the THC percentage. Take a peek at the full cannabinoid profile. You might be surprised by what these so-called “minors” can do.
